Endothelial Defense™ with Full-Spectrum Pomegranate™ and CORDIART™
Item Catalog Number: 01997
Boost Endothelial Function For Vascular Health
Optimal heart health depends on many factors, including proper endothelial function.1 Even with cholesterol/glucose levels in the healthy range, aging individuals need to maintain youthful integrity of their endothelium—the thin layer of cells lining the interior of the entire circulatory system.
Based on published studies showing improvements in endothelial function, health-conscious people have been drinking pomegranate juice or taking a standardized pomegranate supplement.
Going Beyond Pomegranate
The addition of CORDIART™ (extract from sweet orange peels) to pomegranate provides another vascular benefit by activating endothelial production of nitric oxide, which signals the smooth muscles to relax, inducing vasodilation to support healthy circulation.
In clinical research, 500 mg of CORDIART™ alone produced an 18% improvement in flow mediated dilation, a direct marker of endothelial function. CORDIART™ also inhibited the pro-inflammatory factors C-reactive protein and serum amyloid A that interrupt healthy nitric oxide production.2
For those seeking the convenience of three nutrients clinically shown to help with blood flow and age-related changes in endothelial function,2-6 the newly formulated Endothelial Defense™ provides GliSODin®, Full-Spectrum Pomegranate™, and CORDIART™.
The orally active form of superoxide dismutase (SOD)—called GliSODin®—has been clinically demonstrated to support healthy arterial function and structure, while boosting levels of the body’s protective enzymes—SOD and catalase.4-6 The new Endothelial Defense contains a potent dose of GliSODin® along with 500 mg
The new Endothelial Defense™ also provides standardized pomegranate juice extract and a proprietary pomegranate flower and seed oil blend. These extracts from different parts of the pomegranate plant provide potent polyphenols clinically shown to support healthy blood flow, youthful lipid and glucose metabolism, and healthy inflammatory factors.2,3,7-9
Endothelial Defense™ with Full-Spectrum Pomegranate™ and CORDIART™ addresses many factors that promote youthful endothelial function in a dose of two softgel capsules daily.
1. Annu Rev Physiol. 2006;68:51-66.
2. Bioactor B.V.;2013.
3. Altern Med Rev. 2008 Jun;13(2):128.
4. Eur Ann Allergy Clin Immunol. 2007 Feb;39(2):45-50.
5. Phytother Res. 2004 Dec;18(12):957-62.
6. Free Radic Res. 2004 Sep;38(9):927-32.
7. Adv Biomed Res. 2014; 3:100.
8. J Nutr Sci. 2012; 1:e9.
9. Biofactors. 2015 Jan-Feb;41(1):44-51.
Serving Size 2 softgels
Servings Per Container 30
Amount Per Serving
Superoxide Dismutase/Gliadin Complex (GliSODin®) [SOD (Superoxide Dismutase) Enzyme Activity = 500 IU]
POMELLA® pomegranate extract (fruit) [std. to 30% punicalagins (120 mg)]
Pomegranate 5:1 extract (fruit)
Proprietary pomegranate blend (flower extract and seed oil) [std. to 22% punicic acid (30 mg)]
CORDIART™ flavonoid glycoside [from immature sweet orange (peel)] [std. to 90% rutinoside (450 mg)]
Other ingredients: extra virgin olive oil, gelatin, maltodextrin, glycerin, purified water, sunflower lecithin, carob color, beeswax.
POMELLA® Extract is covered under U.S. Patent 7,638,640 and POMELLA® is a registered trademark of Verdure Sciences, Inc.
Isocell SA, France is the owner of US Patents Nos. 6,045,809 and 6,426,068B1 and trademark of GliSODin®.
CORDIART™ is a trademark of BioActor B.V.
Dosage and Use
Take two (2) softgels daily before breakfast, or as recommended by a healthcare practitioner.
Do not take this product if you are allergic to wheat or gluten.
KEEP OUT OF REACH OF CHILDREN
DO NOT EXCEED RECOMMENDED DOSE
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.